A new
development in UVB phototherapy treatment for psoriasis
Br J Dermatol. 1988 Jul;119(1):11-9.
van Weelden H, De La Faille HB, Young E, van der Leun JC.
Institute of Dermatology, State University of Utrecht, The
Netherlands.
We have compared the therapeutic effectiveness of a new
UVB fluorescent sunlamp, the Philips TL-01 lamp, which emits
a narrow peak around 311-312 nm, with the currently used
Philips TL-12 lamp, in 10 patients with psoriasis. We also
compared the tumour inducing capacity of the two lamps in
hairless mice. The therapeutic effect of the Phillips TL-01
lamp was superior to that of the TL-12 lamp in nine of the
10 patients. In the mice, the median tumour induction time
was significantly longer in animals exposed to the TL-01
lamp. Phototherapy with the new type of lamp requires a
higher dose than phototherapy with the usual broadband UVB
sources. In practice this means that more lamps are needed
in the light cabinet. However, the new lamps appear to
provide more effective and safer phototherapy for psoriasis.
PMID: 3408653 [pubMed - indexed for MEDLINE]
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